>Observed mutation frequencies around genes in turn accurately predict patterns of genetic polymorphisms in natural Arabidopsis accessions (r=0.96). That mutation bias is the primary force behind patterns of sequence evolution around genes in natural accessions is supported by analyses of allele frequencies. Finally, we find that genes subject to stronger purifying selection have a lower mutation rate. We conclude that epigenome-associated mutation bias2 reduces the occurrence of deleterious mutations in Arabidopsis, challenging the prevailing paradigm that mutation is a directionless force in evolution.
https://pubmed.ncbi.nlm.nih.gov/35022609/
There goes the neighbourhood, also fuck 4chan's shitty broken spam filter, seriously what the fuck
https://pubmed.ncbi.nlm.nih.gov/35022609/
There goes the neighbourhood, also fuck 4chan's shitty broken spam filter, seriously what the fuck
