Membrane would forget she exists half the time, and would continuously deny that she's an alien to his son>I know it's tough adjusting to a new mother, son, but please refrain from making her feel unwelcome in our household, it's not her fault she was born with a rare skin condition and rubber limbs.
Doof would be a bumbling boyfriend who tries to do right by Spinel but constantly fucks it up. They'd be codependent as fuck.
Eustace would just sit on the couch and yell at Spinel to make him some food. She'll probably snap and try to strangle him after a few days.
Hank whips her into shape and helps her adjust to living a normal life, while Spinel helps Hank loosen up.
Zim has no idea what a relationship entails and just sort of drags Spinel into his schemes.
Bugs finds Spinel too clingy for his tastes and tries to ditch her, only to feel bad and come back to her trying to blow up the earth.
Courage would be a purely platonic relationship that, once he gets over his fear, results in him helping her get over her past trauma.
Professor Utonium is just a nice guy all around to her. He struggles to say no to her but the girls are always around to keep her in check.
Joker corrupts her and turns her into Harley 2.0.
Skeletor does something similar, but their relationship isn't as fucked up.
Kronk is just a generally good guy who gives Spinel a new purpose in helping lead his squirrel scouts, whom she becomes instantly popular with.
I can't see Grievous being in a romantic relationship, and I can't see him giving a fuck about Spinel.
Gaston just sees Spinel as one of dozens of admirers, but he never dumps her because his ego would never allow it.
Batman is annoyed as fuck by Spinel, but slowly warms up to her and begins to respect her abilities.
Grim is used to this bullshit, and is just happy that Spinel, while being a new annoyance, doesn't treat him as a literal slave.
Iroh sits down with Spinel for some tea and helps her while giving her good life advice.