While normally I'd agree with you, this one at least makes some sense.
All the 'lol let's make it edgy' animations just take mario and make him do the funny mushrooms and then haha he kill everyone
This one makes more sense because realistically Wile e coyote would be extremely tired of roadrunner's shit, having chased him for most of his life in vain.
Then when he finally gets him, he lets out all his rage and frustration and just fucking mangles roadrunner.
Only to discover it was all he has left in his life, now he has no purpose. So he starts sobbing and kills himself.
At least that's why I found this one funny.
There's actual thought put into it.