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The entire series is about Stu struggling. His only friends are effeminate beta males, who are equally as lost and hopeless as he is. Stus own father forced himself into his house and leeches off him on daily basis, devoting his remaining days to being a pain in his sons ass till his last breath. His wife is a nagging bitch who is never satisfied, Every day she sees to it that Stuis broken and worn down a little more everyday. She's also too incompetent to raise her children so she has to desperately look for answers from a Quack scam artist.
Due to his inability to create a stable environment, His children are constantly thrown into life threatening emotionally scarring situations. He struggles to make a living by making toys secluded in his basement (Away from his friends and family), similar to a little boy locking himself in his room and playing with plastic soldiers. Perhaps this is him clinging to his childhood; A time when things where much simpler and optimistic. On top of that, He has to deal with insecurities and self loathing that stem from his brother who's successful, rich, and married to a hot wife.
Rugrats is not a series about 4 energetic babies exploring the colorful world around them, It's about a neurotic depressed middle aged man struggling to keep himself from falling apart in the turbulent reality he has been thrown into.