Mario and Luigi (John C. Reily and Will Ferrell) are a couple of low time plumbers with an iq of 48, Mario has a girlfriend, Peach (who unbeknownst to Mario,is actually a hooker and a drunk played by Kathryn Hahn, trying to seduce both brothers to squeeze money out of the two).
One day Mario and Luigi won 100 million from the lottery, so Peach, being the whore that she is, decided to tell her pimp, Bowser (Craig Robinson) and they hatch a plan to leech it off the two plumbers. by pretending that Peach is kidnapped by Bowser.
Meanwhile Mario and Luigi's cousins, Wario (Danny Mcbride) and Waluigi (James franco) hears about their winnings and plan to take it all for themselves, Wario gets himself some mushrooms from his local dealer, 'Toad' (Adam Scott) and laces their spaghetti with the mushrooms, They all start to trip where all they could see in Mario Land where everything is cgi, Mario and Luigi panics and tries to save Peach from Bowser, stopping the whole Drug Cartel and Bowser's child slavery ring in the process
Seth Rogen plays a DEA agent
Terry Crews as King Kong, a rival drug kingpin
Rob Cordry as Bowser Jr
John Lithgow as Bullet 1
Liam Neeson as Bullet 2
Directed by Adam Mckay
