Noticed there's alot of them nowadays like Link and Ruto an elf and a fish girl, Bojack Horseman even a human man married to a deer anthro woman and having kids, Wolf Children's title parents being a human woman and a wolf man, Hatton Slayden's artworks and all that.

I see it as equal to mixing ethnicity or same gender romance. Xenos, anthros, mutants and cyborgs are people who are different.