>>106216962If you're referring to Madoka's witch, then it depends on which loop it is. If it's the Witch of Salvation, then they have a pretty good shot, as they've dealt with planet destroyers before. The Witch of Despair at the end of the anime is infinitely more difficult, and could possibly fuck them before they could react, but the high-tiers could likely stop it before it eats the galaxy.
Ultimate Kriemhild per Wraith Arc bitchslaps them, though.