Yeah, she was some kind of Wonder Woman villain who was like an F-lister.
She gained control over this island and made it a safe-heaven for super villains and mad scientists and the Doom Patrol were staying there to keep from being hunted as terrorists or some such.
After the Chief injected himself with kryptonian DNA to become a Superman and they had to put him in stasis, the blonde lady basically made them her bodyguards and took them to a swanky party in North Korea where she was promptly kidnapped and ended up in a torture rape dungeon for a grand total of like 20 minutes before they saved her.
And at the end of that story, the father of the immortal family implied that it was more than enough time to do something to her, but we never found out what.
Then things had to be wrapped up, so she was possessed by Mr. Somebody so he could gain control over the island's resources in his media campaign to ruin the reputation of superheroes.