The fate of Grimlock and the child are left up in the air, but it opens up future Transformers stories in a major way. If Cybertronians can live in organic hosts and create new Cybertronians through *ahem* traditional means, they completely change everything we know about Transformers and their relationship with life itself.
If the upcoming reboot is more along the lines of the adjustment of 2011’s The Death of Optimus Prime, then the continuity will remain intact. If it’s more of a New 52 style clean slate change, then we may never know the future of Grimlock and his Lone Wolf and Cub style adventures with this new organic Cybertronian. And that would be a shame.