The following genes are present in at least 1/3 of the African population and are known to DECREASE intelligence with genome-wide levels of significance:
rs4640173 (A) Africans are 118% more likely to have this gene than Europeans
rs6736129 (A) Africans are 163% more likely to have this gene than Europeans
rs7019796 (T) Africans are 134% more likely to have this gene than Europeans
rs8138473 (T) Africans are 103% more likely to have this gene than Europeans
rs9755750 (A) Africans are 162% more likely to have this gene than Europeans
rs9939991 (A) Africans are 135% more likely to have this gene than Europeans
• These genes are known to influence mainly the hippocampus, brain, limbic system, central nervous system, cerebral cortex, cerebrum, parahippocampal gyrus, telencephalon, temporal lobe, brain stem, prosencephalon, rhombencephalon, occipital lobe, cerebellum, visual cortex, parietal lobe, retina, basal ganglia, neural stem cells, corpus striatum and frontal lobe.
• These genes alone account already for roughly two thirds of one standard deviation in cognitive ability.
• These genes are at least 50% more likely to exist in one population than in the other, can be found in at least one third of either population, and positively affect Europeans or negatively affect Africans. More than 200 genes that meet these requirements can be conservatively estimated to exist.
• The differences between populations might be even larger since the African sample included cohorts with European admixture.
• Lee, James et al. "Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals." Nat Genet. 2018 Aug;50(8):1112-1121. doi: 10.1038/s41588- 018-0147-3. Epub 2018 Jul 23. Supplementary data.
• The 1000 Genomes Project Consortium, "A global reference for human genetic variation", Nature 526, 68-74 (01 October 2015) doi:10.1038/nature15393. Superpopulations.