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>The brain's overall size begins to shrink when you're in your 20s or 30s, and the rate of shrinkage increases once you reach age 60. Brain shrinkage doesn't happen to all areas of the brain at once. Some areas shrink more and faster than others, and brain shrinkage is likely to get more severe as you get older.

>Brain atrophy — or cerebral atrophy — is the loss of brain cells called neurons caused by ageing. Atrophy also destroys the connections that help the cells communicate.

https://www.healthline.com/health/brain-atrophy