The GF Crew are huge assholes.
>Bill is way more menacing.
>The Twins fight more equally rather than dipper giving up everything.
>The Stans are much less redeemable and Mabel gets what she deserves.
>Tons Of Illegal Shit Everywhere, the town is much more of a shithole.
>Soos is the new Carl.
The Smiths are well adjusted and more functional as a family.
>Beth's issues are much smaller if not completely gone.
>Summer is the same.
>Jerry is a wimpy goofball who will step up for his family when the situation arises, employed and butts heads with Rick.
>Morty still goes to school, is an anchor for Rick instead of a meatshield.
>Rick is about the same but holds back on the sex and murder, more of an arrogant smartass with a soft spot and than a remorseless asshole with a tiny smidgen of a conscience.
>Rick makes a lot more mistakes, but they get out of them with cooperation and teamwork rather than Rick just shitting all over everyone.
>SEVERAL GALLONS OF WHIMSY DUMPED ALL OVER THE PLACE.