>>130242869>Just do a third origin movie for themNo?
Do a movie with them being a famous, beloved group of Science Heroes in alternate NY City, and the Beyonder post Kang decides the multiverse needs "fixing" and does a contest/competition to see what's worth keeping, the classic "battle for the fate of your universe" trope, and the heroes manage to salvage the situation and every unique person gets combined to a single universe, and duplicate people become a fusion of sorts of themselves.
That's a clean answer for Mutants being persecuted in Universe C, (and some of their notable persecutors showing up in Final Universe). Fantastic Four were THE heroes of Universe B, Venom/Morbius in Universe D, Avengers in Universe A.
Now they all co-habitate Final Universe, and you can explore Dark Dimensions/Negative Zones/Microverses or I dunno THE WHOLE GALAXY if you want to tell non-Earth shit.