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They're great. But you should probably find a handful that really work for you and concentrate on utilizing them effectively, rather than trying to make effective use of hundreds.
Whenever I find a brush mega-pack I like, I go through and experiment with all the brushes and save a copy of all the ones I really like for my personal "kit". Usually I end up using less than one-tenth of what's there, but just like wandering through an art supply store, it's better to pick out the supplies that really work for you, than to try and use everything that strikes your fancy.
