If you think that physics is above all the ather science than yes, no game changer since.
Of course every real science stand above physics, but physics is not sufficient in a way. Take the Schrodinger equation for example, it makes the right prediction but it is too complex for modeling simple chemical reactions, so not really applicable/
I would argue that all of Biology since Einstein is pretty revolutionary. Since him the whole field of molecular biolgy was born and blossomed. This is the inner mechanics of Life itself and to me it is really big.
We all take for granted our knowledge about how cells work, the mechanisms of evolution and the diversity of life it produced but all this is the result of all the work of the 19,20th century. Today, we take it for granted than it is in the subconscious of everyone, our whole society, and we our History in a different light. In fact this extend Human history since the origin of life.
Thanks to this research, we can know imagine modigying our genes, solve cancer, maybe even recreate dinosaurs. And guess what ? All the equations of physics are not enough (even if fucking essential).
At the time of Einstein, we reasoned about the Universe in terms of: energy, matter, space, time.
We now have a fifth element: INFORMATION/ COMPUTATION.
1) information is at the absolute heart of life, besides thermodynamics and chemistry.
2) its not just about genes and computers. There is something fundamental about it. We haven't yet put the finger of the nature of information/computation. And I think it is part of the answer to: "The Unreasonable Effectiveness of Mathematics".