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So far it's known that the AZ vax is the least safe. This is because it uses natural viral spike, whereas the mRNA vaxes and the J&J vax use spikes with proline substitutions for what's known as prefusion conformational stability, giving them an extra safety net if they enter the bloodstream. Once it was discovered that the viral spike itself is destructive to the cardiovascular system, there was a bit of a hand-waving push from science writers asserting that the vax is membrane-bound at the injection site, which left a lot of rigor to be desired, for there are 1,001 ways the vax can enter the bloodstream, even if it's just shitty injection technique.
