If the simulation hypothesis were true, then the universe would be able to be "hacked" in a way similar to a computer. All logically consistent computers have at least one vulnerability, and it seems that's fundamental to computers. Yet what we've seen is that the universe it's explicitly impossible to bypass the laws of the universe, faster than light communication isn't possible, you can't solve the halting problem, certain quantum mechanical systems contain uncomputability. This indicates the universe lacks logical consistency SOMEWHERE, ergo it can't be constructed from computation.