>>13272164interpretation of quantum mechanics, the hard problem of consciousness, natural constants (like the speed of light and shit), and if science is to be extended to "everything" like most people do these days, ontology in general. i don't know enough about relativity to say but from my layman's understanding even the (well-substantiated) interpretation of that raises a dire need for a "greater ontological mechanism" that science might not be able to provide.
really anything that has to do with the epistemic limits of science (that humans have been fast approaching in recent decades) is going to crash hard and fast into philosophy.
epistemology OUGHT to be pretty central to scientific thought in general, but the practical results of science causes a blinding effect that makes most people not care or worry. we are starting to be forced to recognize this and reckon with it.