>observed the same behaviors in several generations of their descendants not directly administered the drug."
>"The Ritalin-treated males showed less inhibition than expected when moved to a new environment," said De Serrano. "Under natural conditions, guppies would be expected to freeze if they found themselves in such a situation, as this allows them to assess their new surroundings for predators and other threats."
>De Serrano then produced three generations of offspring from these individuals to see if the behavior of their descendants differed from descendants of those not exposed to the drug and observed behaviors similar to those of first-generation males exposed to the drug.
>"It suggests that Ritalin has the potential to cause changes that persist across several generations,"
>It has been suggested that Ritalin could cause transgenerational effects because MPH has been shown to affect the sperm cells of male rodents. Further, paternal effects have been observed in descendants of rats exposed to drugs with a similar mode of action. Despite these concerns, the transgenerational effects of paternal exposure to MPH in humans are unknown.
>"Because reduced caution in new situations has been associated with increased drug-seeking behavior in rodents and humans, our results suggest that long-term exposure to Ritalin could increase the propensity for drug abuse and other affective disorders in males and their descendants."
https://medicalxpress.com/news/2021-06-guppy-adhd-drugs-affect.html
>"The Ritalin-treated males showed less inhibition than expected when moved to a new environment," said De Serrano. "Under natural conditions, guppies would be expected to freeze if they found themselves in such a situation, as this allows them to assess their new surroundings for predators and other threats."
>De Serrano then produced three generations of offspring from these individuals to see if the behavior of their descendants differed from descendants of those not exposed to the drug and observed behaviors similar to those of first-generation males exposed to the drug.
>"It suggests that Ritalin has the potential to cause changes that persist across several generations,"
>It has been suggested that Ritalin could cause transgenerational effects because MPH has been shown to affect the sperm cells of male rodents. Further, paternal effects have been observed in descendants of rats exposed to drugs with a similar mode of action. Despite these concerns, the transgenerational effects of paternal exposure to MPH in humans are unknown.
>"Because reduced caution in new situations has been associated with increased drug-seeking behavior in rodents and humans, our results suggest that long-term exposure to Ritalin could increase the propensity for drug abuse and other affective disorders in males and their descendants."
https://medicalxpress.com/news/2021-06-guppy-adhd-drugs-affect.html
