Moderna announced that “as of April 13, all placebo participants have been offered the Moderna covid-19 vaccine and 98% of those have received the vaccine.”
In other words, the trial is unblinded, and the placebo group no longer exists.

How the FDA will weigh the loss of blinding and placebo controlled follow-up is unclear, but just months ago the agency said these trial properties were vital.

“Continuation of placebo controlled follow-up after EUA will be important and may actually be critical to ensure that additional safety and effectiveness data are accrued to support submission of a licensure application as soon as possible following an EUA. … Once a decision is made to unblind an ongoing placebo controlled trial, that decision cannot be walked back. And that controlled follow-up is lost forever,” the FDA said last October.3

At its next advisory committee in December 2020, the FDA reiterated the importance of the placebo group: “Placebo controlled follow-up can be very important in showing that whatever happened in the vaccine group also happened in the placebo group. Because that’s our best way of knowing.”


No biodistribution studies have been conducted for any of the three vaccines currently authorized in the US.
Regulators accepted biodistribution data from past studies performed with related, mostly unapproved compounds that use the same platform technology

https://www.bmj.com/content/373/bmj.n1244

So basically this means we will never know about any long term (+6 months) side effects?
Thoughts?