>>13137729It means it’s a wild experiment.
You’d have to be more specific, if you want me to elaborate. Because it’s not right place to write an advanced immunology, cell biology and molecular chemistry textbook.
>>13137762>it is a "modified uracil" it was replaced with pseuduracil to reduce immunogenicityI assume your question to be serious. It’s a big issue because we have no clue, what really happens. We just have some evidence pointing towards it being less susceptible to RNase. Which are ubiquitous and destroy foreign or harmful mRNA, but we don’t exactly understand, how the selection works. There are a lot of things that could go wrong. And many more we can’t even conceptually grasp yet.
>contains adjuvants for this purpose so there cannot be any adverse reaction by the immune system. You are ill informed. AZD1222/ChAdOx1 nCoV-19 and other viral vector based vaccines allegedly against SARS-CoV-2 don’t contain any adjuvants. Basically you don’t need them, because the immunogenic stuff is already in the cell cultures (HEK-293-T-REx cells) and in the substances needed to keep the vector viable.
>what effects? whats the concern thereAll bets are of. To put it in very simple terms. Basically next time your body wants to get rid of harmful substances - which mostly happens during late autumn, winter and spring - it could cascade into a massive attack on your own cells. Amongst many other possible scenarios.
