Addressing Cancer with Pseudoglucose Introduction to Frustrate ATP Production in Tumor Cells
While ordinary, healthy cells in the human body enjoy a reasonably efficient glucose-ATP conversion, creating on average 36 ATP molecules for every glucose, tumor cells across all classes of cancer have a notoriously inefficient process of glycolysis, creating about four ATPs for each glucose. It has long been standard treatment protocol to keep cancer patients on sugar-free, low-calorie diets in order to slow tumor growth.
Taking this into consideration, one simple proposition for addressing cancer would be to flood the body with synthetic molecules that are chemically similar enough to glucose that they would be accepted by the mitochondria of all cells in the human body including tumor mitochondria. Where healthy cells enjoy an efficient glucose-ATP conversion process that would likely be able to support normal healthy function of non-tumor cells even while withstanding the flood of these synthetic molecules that may be termed, "pseudoglucose," tumor mitochondria would likely be quickly overwhelmed by these 'junk' molecules which would, in effect, cause the engine of cellular metabolism to sputter and stall, leading eventually to cell apoptosis. This effect is not dissimilar to the way in which a six cylinder engine may be able to function adequately with only five cylinders firing, but a four cylinder engine would most likely stall with a cylinder 'down.'
While ordinary, healthy cells in the human body enjoy a reasonably efficient glucose-ATP conversion, creating on average 36 ATP molecules for every glucose, tumor cells across all classes of cancer have a notoriously inefficient process of glycolysis, creating about four ATPs for each glucose. It has long been standard treatment protocol to keep cancer patients on sugar-free, low-calorie diets in order to slow tumor growth.
Taking this into consideration, one simple proposition for addressing cancer would be to flood the body with synthetic molecules that are chemically similar enough to glucose that they would be accepted by the mitochondria of all cells in the human body including tumor mitochondria. Where healthy cells enjoy an efficient glucose-ATP conversion process that would likely be able to support normal healthy function of non-tumor cells even while withstanding the flood of these synthetic molecules that may be termed, "pseudoglucose," tumor mitochondria would likely be quickly overwhelmed by these 'junk' molecules which would, in effect, cause the engine of cellular metabolism to sputter and stall, leading eventually to cell apoptosis. This effect is not dissimilar to the way in which a six cylinder engine may be able to function adequately with only five cylinders firing, but a four cylinder engine would most likely stall with a cylinder 'down.'
