>>13044328Besides sterilizing the tall men and short women, you knock in genes on the Y chromosome which code for reducing growth hormone while coding the general DNA for making people large. So people with Y chromosomes (males) will not be big but people with no Y chromosome (females) will not have their hormones modulated and they will become really big.
Maybe something like attaching the genes that code for multiple epiphyseal dysplasia onto the Y so that all males are affected by it if that is even possible. but this affects joint health so thats probably not a good way to go about it. Unless there was another gene that codes for dense bones and joints that you could also append in order to offshoot the negatives.
This of course is not easy to do.
>>130444281 generation, assuming you modify the germline of your whole population. Also, because the germline is modified, all future generations will also have it, and all future women will be big and men will be small.