and beta-amyloid proves to be some last ditch protein produced to protect the brain from infectious microorganisms (like HSV-1 and 2) that a younger immune system would normally keep at bay--they'll never admit it, will they?
These people have too much invested in the amyloid hypothesis at this point.
Too many papers, too many grants, too few tenure-track positions to scramble for.
These people will literally make hundreds of millions of people and their families suffer horribly, just for the sake of career advancement.