>>12980168>I'm not saying a worsening of disease due to vaccines isn't a possibility, I just don't like the discussion of it being an inevitability for SARS-CoV-2.The human population is far too large is the problem. Consider, for instance, of the virus as like boats. If, hypothetically, the human population was only a thousand people, Covid's genetic pool is like a canoe, small, can turn on a dime, highly effected by extrinsic factors like population density, viral lethality and so forth. Right now, with 8 billion people, the virus' genetic pool is like a battlecruiser, large, and if it changes direction then it really can't be stopped by anything short of a tactical missile.
>which could mean that the issue is that we've been selectively breeding chickens to be less capable of coping with the diseaseSeems possible, but that could only be found out by looking at the lethality of the disease in wild bird populations which host the disease naturally. Though consider that Marek's disease changed into this after a couple decades, about 20 chicken generations, I don't think we've changed chicken genepools enough in that time to allow for that, and it's not exactly clear what traits could lessen natural Marek's resistance, especially to such a degree that it has near 100% mortality, and the mortality rate seems to be near-universal across every flock in the world. It just doesn't seem likely to me at all.
>https://www.cdc.gov/flu/about/burden/index.htmlThe later years look worse to me, idk, but it'd probably require more in depth analysis. It's only a theory though, widespread commericial influenza vaccinations are fairly recent phenomena and only given to a minority of people, we'd have to look at how the flu evolved in the coming decades to know for sure.