Turning back the epigenetic clock to rejuvenate

No.12882009 ViewReplyOriginalReport
Quick rundown

>A hallmark of ageing is epigenetic changes that turn off genes in cells and cause them to lose their functions
>These functional losses eventually result in the symptoms of old age like worse wound healing and the degeneration of tissues
>Scientists managed to revert these epigenetic changes in aged mice
>The nerve cells in the treated mice showed a youthful ability to regenerate themselves
>The epigenetic profile of the treated cells were also that of naturally young cells

The way they "rejuvenated" the mice cells was by the method used to revert adult cells into induced pluripotent stem cells (they used yamanaka factors). Except this time, it was done in short bursts so that the cells didn't revert all the way back to stem cells which would've potentially caused cancer. The result was this rejuvenating effect with no signs of cancer within a year.

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