>>12761500I'm on 100mg for the last 8 months and I'm feeling bretty good. I used to take fluvoxamine which made me very sleepy, almost narcoleptic, but sertraline seems to work fine in terms of minimising depressive and anxious symptoms. It's not a cure-all though, you need to actually make improvements to your life to alleviate depression. Idk what kind of brain damage can occur, but 200mg might be too much if you're feeling side effects