Why does COVID selectively target Europeans?
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https://www.medrxiv.org/content/10.1101/2020.04.05.20054627v3.full.pdf
>We found significant positive correlation (r=0.58, P=0.03) between West European hunter 64 gatherers (WHG) ancestral fractions and COVID-19 death/recovery ratio for data as of 5th65 April 2020. This association discernibly amplified (r=0.77, P=0.009) upon reanalyses
>Finally, six immune system related SNPs (rs2243250, rs1800872, rs1800896, 340 rs1544410, rs1800629 and rs1805015) that display significant variability between Europeans 341 and East Asians (Odds Ratio>2, Chi square>40, P<10-10)are likely associated with the 342 development of immune responses in the first year of life
>Consequently, WHGs who contributed discernible ancestry fractions to most 426 Europeans, provided very low fraction (<10%) of the same in the ancestries of Near 427 Easterners (Turkey, Georgia and Armenia) [37]. Consistent with this, COVID-19 428 death/recovery ratio in Turkey, Georgia and Armenia remained discernibly lower compared 429 to most European countrie
TLDR; more western ancestry = greater susceptibility to covid
>b-b-but indians in london were more likely to die
yes, due to low vitamin D. Correct the D and whites die more.
You can also see this trend in the US--Asians have a slightly lower deaths/capita than whites, DESPITE the fact that ALL Asians live in the city, while most whites live in rural isolated areas. Meaning the effective death rate is much lower in Asians.
Another weird trend is that African-Americans have a very high death rate from this, as opposed to Africans. Latinos too, it seems. However, actual Africans don't seem to be hit much at all. It's almost as if recent racial mixture is also a type of risk factor, maybe wonking up some immunity genes?
>We found significant positive correlation (r=0.58, P=0.03) between West European hunter 64 gatherers (WHG) ancestral fractions and COVID-19 death/recovery ratio for data as of 5th65 April 2020. This association discernibly amplified (r=0.77, P=0.009) upon reanalyses
>Finally, six immune system related SNPs (rs2243250, rs1800872, rs1800896, 340 rs1544410, rs1800629 and rs1805015) that display significant variability between Europeans 341 and East Asians (Odds Ratio>2, Chi square>40, P<10-10)are likely associated with the 342 development of immune responses in the first year of life
>Consequently, WHGs who contributed discernible ancestry fractions to most 426 Europeans, provided very low fraction (<10%) of the same in the ancestries of Near 427 Easterners (Turkey, Georgia and Armenia) [37]. Consistent with this, COVID-19 428 death/recovery ratio in Turkey, Georgia and Armenia remained discernibly lower compared 429 to most European countrie
TLDR; more western ancestry = greater susceptibility to covid
>b-b-but indians in london were more likely to die
yes, due to low vitamin D. Correct the D and whites die more.
You can also see this trend in the US--Asians have a slightly lower deaths/capita than whites, DESPITE the fact that ALL Asians live in the city, while most whites live in rural isolated areas. Meaning the effective death rate is much lower in Asians.
Another weird trend is that African-Americans have a very high death rate from this, as opposed to Africans. Latinos too, it seems. However, actual Africans don't seem to be hit much at all. It's almost as if recent racial mixture is also a type of risk factor, maybe wonking up some immunity genes?
