It's funny, I recall reading posts from around 2008-2014 where people hypothesized that you could grow a bigger penis by inhibiting or weakening the crosslinking of collagen and elastin, which is exactly was done in the study.
There was a guy who injected chemicals into his penis with the same goal and mechanism of action in mind. He injected papaverine which causes intense erections and also weakens collagen like in the study. He didn't use a vacuum device but his idea was that the long lasting erections from the papaverine would exert force on the tunica albuginea and buck's fascia of the penis. He did this for several months and documented his gains, he went from 7.5x5in to 9.5x6.5in with picture proof. I can link his posts if anyone wants.
This study seems to confirm such a penis enhancement method works, what a funny coincidence
