>>12629546We can do engineering all the way down to the atomic scale. The reason is that life is made of atoms, and biology is complicated processes capable of general purpose computation, so atoms can do complicated things. There is no reason that we should be able to do engineering with nuclei, because our universe doesn't embed life in nuclear structures.
But that doesn't mean that you can't try. Suppose you could build a pion laser, and stabilize it by the appropriate methods, by surrounding it with the appropriate reflectors to prevent 2-photon decay, or change to charged pion very quickly to prevent decay, or ... I don't know, or else this wouldn't be speculation. Then you would be able to do nuclear engineering, meaning move nuclei around like you move atoms with light lasers, and pump energy into hadronic states at will, not by collisions, but by engineering. Without good bosonic fields which you can manipulate over relatively large scales, there is no hope for any of this.
Using a pion laser, you might be able to blow up elementary particles in a spherically symmetric way, like balloons, and let them collapse onto themselves to make black holes. This requires a controlled implosion, because the mass of a nuclear scale black hole is that of a mountain. If you can somehow make a symmetric implosion which shrinks the pumped up hadron by 10 orders of magnitude, to get some black hole states at some heavy but achievable mass, you can make monopoles, black holes, strings, and turn anything into energy.