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Anonymous Thu 14 Jan 19:59:44 2021 No.12581751 View Reply Original Report

Quoted By: >>12581795 >>12582030 >>12582290 >>12583813

I have 2 questions regarding the mRNA vaccine:

If you happen to be infected with another virus that has reverse transcriptase activity while you get the vaccine, could the mRNA be integrated into your DNA?

2. The vaccine is made so that the mRNA resists getting destructed before it reaches the cell, will it not also resist getting destructed after it’s been translated?

Anonymous

Anonymous Thu 14 Jan 2021 20:08:00 No.12581795 Report

Quoted By: >>12581808

>>12581751
>could the mRNA be integrated into your DNA?
It. Is. Impossible. Really. Impossible. They have (obviously) specifically chosen a sequence that cannot be integrated into the DNA.

>will it not also resist getting destructed after it’s been translated?
It is eliminated very quickly. Do you think the vaccine you were given 10 or 30 years ago is still circulating in your body?

Anonymous

Anonymous Thu 14 Jan 2021 20:12:32 No.12581808 Report

Quoted By:

>>12581795
>a sequence that cannot be integrated into the DNA.
No such thing lol

Anonymous

Anonymous Thu 14 Jan 2021 21:13:27 No.12582030 Report

Quoted By: >>12582074

>>12581751
1) There is a possibility that it can be integrated into your DNA--the question is, will it undergo TC/TL? Probably not because there's no use for it, and even if it did, the spike protein would be the only product.
2) No; there are two known lipids which are surfactants which are designed to vehicle the mRNA into the cell. Once they interact with the phospholipid layer of the cell, they will have nothing to do with the mRNA. The mRNA will simply use the ribosomes in your cells to produce the spike protein, nothing else. The only issue is the metabolic degradation of the lipid surfactants that are being used in the current Pfizer vaccine.

Anonymous

Anonymous Thu 14 Jan 2021 21:23:29 No.12582074 Report

Quoted By: >>12582110

>>12582030
>There is a possibility that it can be integrated into your DNA--the question is, will it undergo TC/TL? Probably not because there's no use for it, and even if it did, the spike protein would be the only product.
Jesus Christ. Autoimmune disease just waiting to be formed if your producing spike protein all the time.

Anonymous

Anonymous Thu 14 Jan 2021 21:31:10 No.12582101 Report

Quoted By:

gonna get the vaccine next week
am i gonna be a NPC /sci/?

Anonymous

Anonymous Thu 14 Jan 2021 21:33:50 No.12582110 Report

Quoted By: >>12582135 >>12582304

>>12582074
The likelihood of this is close to zero. There's no functional use to produce the protein when the cell is undergoing replication. Not everything in your DNA gets transcribed, let alone translated. It only occurs when there's a NEED for it.

Anonymous

Anonymous Thu 14 Jan 2021 21:38:26 No.12582135 Report

Quoted By: >>12582156 >>12582184

>>12582110
Complete fool here
How does the body know it's not needed? It is not familiar to this spike protein, right? It just learns to produce it, how are we assuming or know that our body (DNA) learns when it is appropriate to produce? Isn't this a novelty?

Anonymous

Anonymous Thu 14 Jan 2021 21:46:18 No.12582156 Report

Quoted By: >>12582164

>>12582135
Often times, tissues send out signals (release molecules) into the extracellular/intracellular matrix which either promote the production/non-production of something via negative/positive feedback loops. For these substances to be produced, these signals cascade into more and more which eventually tell cells to transcribe and translate certain sequences of your DNA, and this is how proteins (enzymes, structures, or other substrates). In this case of the spike protein, since there really is no use for it in the body (waste of material and energy), it'll ignore it when DNA is undergoing TC/TL. There are many checkpoints in the replication of DNA that prevent unnecessary products from being formed. Only required substrates will be encoded for and others will be overlooked.

Anonymous

Anonymous Thu 14 Jan 2021 21:47:35 No.12582164 Report

Quoted By:

>>12582156
...and this is how proteins (...) are made.

Sorry, I'm on my phone.

Anonymous

Anonymous Thu 14 Jan 2021 21:52:56 No.12582184 Report

Quoted By:

>>12582135
Basically, nothing demands for that specific sequence (and eventual structure) to be produced.

Anonymous

Anonymous Thu 14 Jan 2021 22:19:13 No.12582290 Report

Quoted By:

>>12581751
LETS ALSO TALK ABOUT THE ASTRAZENECA VACCINE WHICH HAS LITERAL DNA ALREADY IN IT

Anonymous

Anonymous Thu 14 Jan 2021 22:22:55 No.12582304 Report

Quoted By: >>12583730 >>12583735

>>12582110
>The likelihood of this is close to zero.
You make this claim but how do you know? Just because you think it might not get transcribed doesn't mean thorough testing shouldn't happen before its released. It sounds risky AF. Inject at your own risk.

Anonymous

Anonymous Fri 15 Jan 2021 06:16:20 No.12583730 Report

Quoted By:

>>12582304
"is CLOSE to zero" not saying it's zero, but very unlikely. I can make this claim because there's many instances where we have tested for this, and often times things are not produced simply because they're introduced into the body. I'm not trying to claim the vaccine is safe, I'm simply saying that the mRNA notion of it integrating into your DNA is far-fetched, any person with a BS in biology can tell you this.

Anonymous

Anonymous Fri 15 Jan 2021 06:19:58 No.12583735 Report

Quoted By:

>>12582304
I also agree that not enough testing was done on these vaccines to warrant positive public sentiment, however, it's being pushed as something that is safe and effective given the headlines that are being pushed out. This technology isn't experimental (mRNA therapy), but the fact that it was rushed out and not fully tested for is what worries me. The only thing I am against are the ridiculous notions that are being spread on this site and other forums that can easily be denounced with simple biochemical understanding.

Anonymous

Anonymous Fri 15 Jan 2021 06:58:24 No.12583813 Report

Quoted By:

>>12581751
>If you happen to be infected with another virus that has reverse transcriptase activity while you get the vaccine, could the mRNA be integrated into your DNA?
No. Retroviruses also use things like integrases to inject cDNA into a genome. It's just not so easy to take mRNA, reverse-transcribe it to cDNA, move that cDNA into a host cell nucleus, integrate it, and then have it transcribe back into functional RNA. We've been following HIV for almost 40 years, it's not like we haven't been looking for this.
Not only that, but mRNA vaccines are selectively taken up by dendritic cells, not CD4+

The vaccine is made so that the mRNA resists getting destructed before it reaches the cell, will it not also resist getting destructed after it’s been translated?
It does resist being deteriorated. The median half-life for mRNA is typically around 10 hours or so for humans. The mRNA delivered in the vaccine is far more stable - it lasts for a day or two. That's it. And in order to achieve that stability, it must be kept at -80 degrees with lipid nanoparticles. By the time your body's humoral response matures, the mRNA is long gone, and most of the spike protein is, too.

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