https://sci-hub.se/10.1089/rej.2015.1763
Whole body induced cell turnover. I just read the paper and there's literally no reason this couldn't work if we put the manpower and elbow grease into getting it done. This is way more feasible than anything the biogerontology community or Aubrey de grey has come up with. The only obstacle stopping this from getting done is funding and willpower; imagine if Google's calico worked on this instead of wasting their time on alzheimers drugs. Still, this will require billions to accomplish, but I think there is a high probability of success. If we succeeded at this we would significantly delay death, but of course we would still need to address cancer and extracellular waste products that would still not be deleted even though we replaced the cells that had intracellular garbage in them. Another problem is that this wouldn't work for exceptionally long cells like motor neurons, that grow in length as the embryo develops and matures. But, this would still buy us a lot of time, and cells such as motor neurons would at least be significantly more supported by surrounding cells which would provide a better homeostatic environment. We could easily get some people an extra 50 years of lifespan with this. Thoughts? Are there any holes in this?
Whole body induced cell turnover. I just read the paper and there's literally no reason this couldn't work if we put the manpower and elbow grease into getting it done. This is way more feasible than anything the biogerontology community or Aubrey de grey has come up with. The only obstacle stopping this from getting done is funding and willpower; imagine if Google's calico worked on this instead of wasting their time on alzheimers drugs. Still, this will require billions to accomplish, but I think there is a high probability of success. If we succeeded at this we would significantly delay death, but of course we would still need to address cancer and extracellular waste products that would still not be deleted even though we replaced the cells that had intracellular garbage in them. Another problem is that this wouldn't work for exceptionally long cells like motor neurons, that grow in length as the embryo develops and matures. But, this would still buy us a lot of time, and cells such as motor neurons would at least be significantly more supported by surrounding cells which would provide a better homeostatic environment. We could easily get some people an extra 50 years of lifespan with this. Thoughts? Are there any holes in this?
