>>12487541Probably not. The mutations are on the receptor binding domain of the spike protein. Two of them give it slightly higher binding affinity to the ACE2 receptor, and one is probably not functional. The antibodies that are produced as a result of the virus bind to the spike protein RBD as well, so these mutations in all likelihood result in stronger antibody binding also. So the vaccine might work a little better, but at least probably won't be any less efficient. The bigger issue is that if it really is more contagious (we still need more data to be sure that it is), it'll be harder to contain.
