>>12481767I don’t mean to be condescending, but based on the question I don't think you understand what I was saying.
CRISPR is a bacterial/archaeal immune system that breaks apart foreign DNA in a cell. It is used in editing genes by targeting that break to the host cell's genome. You also insert DNA into the cell that is almost a match the the gene you want to edit, and in a very small percentage of cells, normal processes will switch the copy you inserted for the original one.
The CRISPR target has to be part of the section of gene that is changed, so that cells that are not edited get killed by the CRISPR system (because their DNA is broken apart by CRISPR) and cells that did swap their gene out for your changed version survive.
So, CRISPR doesn't actually make the change in the gene, it just kills cells that didn't make the change themselves.
I might have misunderstood your question, though. If I did, sorry
