No.12407414 ViewReplyOriginalReport
Scientifically, what's going on in depression?

We know on a macroscopic level, people don't "feel" good and this effects their behavior and sometimes is so overwhelming they end their lives. There is also as far as I'm concerned a kind of stigma that depression can be treated but not really ever cured.

We know on a microscopic level, concentrations of neurotransmitters and other metabolites are different than those of "healthy" people.

On an intermittent level, studies like fmri show differential activities in various areas of the brain between the two classes of brains.

1, what causes it? And a simple answer like extreme hardship in life is not a good answer at all.

2 is it like an injury? If so, injuries should heal and especially with some medical attention should heal completely and more quickly. If it's not like a injury and more like a disease yet again we go back to what is causing it? Babies don't have depression. And I don't wanna hear any of your bs babies born to depressed moms show higher cortisol. Followimg out some basic logic it seems like at some point in adolescence you can develop a brain disease that by current medical technology is not very effective to be treated.

3 and finally, shouldn't you in theory be able to take actions that change the concentrations of your neurotransmitters, train the underperformimg portions of your brain and work on changing your attitude and perspective? Wouldn't those things be difficult but really instrumental in amelioratimg your depression? If you're in really bad shape because you're super fat, it will take a lot of hard work and discipline and Time, but you can get back into physical shape. Why is the same not true of mental health. Or rather why is it sold like it's not possible? Is it all just a pharma scheme? Are the people who are depressed too mentally incapacitated to show the discipline required to do the hard work to get better?

I'm very confused why this is supposedly an incurable disease