>>12392740>How many and what types of cells does the Covid mRNA vaccine modify?Depends on the vaccine. Usually the vaccine is correctly named after the virus and not the disease it causes. SARS-Cov-2 a type of Betacoronaviruses and the disease spectrum it causes is called COVID-19. There are different vaccines not all mRNA vaccines. Normal (attenuated virus and inactivated virus based) ones will also be there in some time. Than there are the vector vaccines like the chimpanzee Adenovirus (Oxford) and the with two human Adenoviruses (Sputnik 5 I think it’s developed by Vector). With the mRNA ones we are talking about either directly injecting the mRNA or mRNA in a nano coating. What does happen with mRNA isn’t completely clear, but most experts agree it’s something along the lines of endocytosis after which it’s translated at the ribosome (like „normal“ mRNA) into proteins. Hence it doesn’t modify the cell since it shouldn’t be reverse transcript into DNA. After the proteins are there specific immun cells, which recognize the proteins as foreign and activate immune cells specialized in destroying or neutralizing foreign stuff. After a certain time the immune system has specific neutralizing antibodies (IgG) and also specific t killer cells. And since there will be cells that recognize the virus if it comes along in the future and activate the specific measures some memorizing immun cells will be the only cells modified. I forgot to mention that you usually chose the mRNA based on certain matrix, coat or spike coding sequences in the virus genome, which if counteracted by the immune system render the virus unable to really get much of an infection going. Also remember any virus infection means the virus „highjacks“ the machinery of the infected cell.
