>>12391681>The shorter the time-frame between the "drug taking" behaviour and the reward the easier it is for your brain to link the reward with the drug-taking behaviour. this is true but it's compounded by and probably outweighed by the more concentrated bioavailable dose and the neurotransmitter activity that will ever occur for the dose essentially happening all at once
oral is kind of like a lit gas cooker under a pot that slowly boils and insufflation/inhalation/injection is kind of like lighting the entire gas reserve and the cooker immediately exploding
and compounding the stronger, quicker effect, it also fades much sooner and more dramatically, both of which cause a stronger urge to redose. and it probably downregulates, depletes, damages, and even kills some neurons (like some dopaminergic ones), which may make the comedowns and withdrawals even worse, making the urge to redose even stronger
combined with the immediate pavlovian association you mention, it's hard not to get addicted
all of this applies even to cigarettes, and is why cigarettes are so addictive while slow-release nicotine patches aren't addictive for most people. also why you can regularly take adderall and even meth in pill form and not develop much addiction, but smoking either one will quickly land you on Cops
