>>12162055LSD is produced semi-synthetically from Ergotamine. You hydrolyze the amine yielding lysergic acid, which you then couple with Diethylamine. The chemistry involved isn't difficult, but the things you handle are sensitive to light, moisture and oxygen, especially the end product. So you need to do it under inert conditions.
LSD is also an incredibly unpleasant chemical to work with, for obvious reasons.
>>12162107No, it's not that hard at all. The problem is getting the precursor, which you have to grow ergot for and ergot is really, really toxic.
Total synthesis of lysergic acid is a PHD in scale. There is a nice publication by Woodward of it out there.
>>12162349Anon, your lysergic acid is not going to survive the acyl chloride approach. You need something gentler.
>oxalyl chloride Just buy thionyl chloride wtf
it's way cheaper