>>12009763No, this is an arbitrary accident of our having evolved with ten fingers and only having cognition enough for about 8-12 things in short term memory (and that's pushing it) at any given time. It is tenable to discuss the intrinsic mathematical advantages of this-or-that base, either independently of human cognitive ability, or taking the latter into consideration.
In applications, I particularly like the RRGGBB convention, relying on hex, to indicate a color. Merely glancing at such an indicator gives you a priori information on what sort of color to expect, assuming your color theory is fair and you aren't some color blind freak.