/sci/ - Science & Math » Thread #11876153

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Anonymous Tue 07 Jul 05:12:15 2020 No.11876153 View Reply Original Report

Quoted By: >>11876154 >>11877577

Daily reminder that curing cancer is important not because of those afflicted with the disease because it will allow us to travel long distances in space without dying from the cosmic radiation.

Anonymous

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Anonymous Tue 07 Jul 2020 05:14:36 No.11876154 Report

Quoted By: >>11876173 >>11876235 >>11876257 >>11876440 >>11878109

>>11876153

Anonymous

Anonymous Tue 07 Jul 2020 05:20:39 No.11876173 Report

Quoted By:

>>11876154
DUDE

Anonymous

Anonymous Tue 07 Jul 2020 05:53:23 No.11876235 Report

Quoted By: >>11876265

>>11876154
Youtube isn't a source

Anonymous

Anonymous Tue 07 Jul 2020 06:04:47 No.11876257 Report

Quoted By: >>11876294 >>11876655 >>11878109

>>11876154
Molecular Biology graduate here. Can confirm that this image is all you need and OP's "science" is useless.

Anonymous

Anonymous Tue 07 Jul 2020 06:06:07 No.11876265 Report

Quoted By:

>>11876235
????????????????

Anonymous

Anonymous Tue 07 Jul 2020 06:08:38 No.11876274 Report

Quoted By:

I'm going to hunt, slay, skin, cook, and eat the person who made this disgusting chart. Consider yourself lucky that this was not you though of course I am humane towards all of the game that I catch.

Anonymous

Anonymous Tue 07 Jul 2020 06:15:14 No.11876294 Report

Quoted By: >>11876521

>>11876257
>OP's science is useless.

To quote OP:
>Daily reminder that curing cancer is important not because of those afflicted with the disease because it will allow us to travel long distances in space without dying from the cosmic radiation.
That's just a statement, and there's nothing of scientific value in that statement. OP's statement isn't something which can even remotely help science to cure cancer. It's just that, a statement.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:26:27 No.11876440 Report

Quoted By: >>11876443 >>11876521 >>11876699

>>11876154
Let's start out by reviewing the paradigm change occurring right now in cancer research:

> The Pharmaceutical Giants Are "Scanning the [Microbiome] Space" for a Cancer Cure

> "How Gut Bacteria Are Shaking Up Cancer Research (Makiko Kitamura, March 13, 2016)

> Top scientists at Roche Holding AG and AstraZeneca Plc are sizing up potential allies in the fight against cancer: the trillions of bacteria that live in the human body.

> 'Five years ago, if you had asked me about bacteria in your gut playing an important role in your systemic immune response, I probably would have laughed it off,' Daniel Chen, head of cancer immunotherapy research at Roche’s Genentech division, said in a phone interview. 'Most of us immunologists now believe that there really is an important interaction there.'

> Two recent studies published in the journal Science have intrigued Chen and others who are developing medicines called immunotherapies that stimulate the body’s ability to fight tumors.

> In November, University of Chicago researchers wrote that giving mice Bifidobacterium, which normally resides in the gastrointestinal tract, was as effective as an immunotherapy in controlling the growth of skin cancer. Combining the two practically eliminated tumor growth. In the second study, scientists in France found that some bacterial species activated a response to immunotherapy, which didn’t occur without the microbes.

> That has increased drugmakers’ interest in the human microbiome -- the universe of roughly 100 trillion good and bad bacteria, fungi and viruses that live on and inside the body. Roche is already undertaking basic research in the field and plans to investigate the microbiome’s potential for cancer treatment, Chen said.

> *'Certainly, we are already scanning the space for interesting opportunities as the science continues to emerge,' he said. 'We are very interested in testing these in a controlled setting.'

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:27:29 No.11876443 Report

Quoted By: >>11876446 >>11876521

>>11876440

> Some experienced investors are skeptical and see the possibility of an approved product for cancer to be at least five years away.

> 'To therapeutically influence the microbiome long-term in humans is a big hurdle,' said Sander van Deventer, managing partner at venture-capital firm Forbion Capital Partners. 'The microbiome is very stubborn. Everything we’ve done so far has only had a temporary effect.'

Cancer as a Fungus

> Cancer is a Fungus: A Revolution in Tumor Therapy, Dr. T. Simoncini, pages 99-115

> "it is useful to remember the example of heliobacter pylori, a micro-organism whose pathogenic value has always been neglected, and which turned out to be the causal agent for gastric ulcers.

> In view of the data available, the answer for neoplastic disease may be hidden in one of the elements of microbiology, that is, bacteria, viruses, or mycetes."

> DEFINITION: "Neoplastic disease is the excessive division of cells, due to a variety of causes, that results in the formation of atypical bodies of tissue called neoplasms. A neoplasm can form virtually anywhere in the body and is commonly referred to as a tumor."
http://www.wisegeekhealth.com/what-is-neoplastic-disease.htm

> DEFINITION: "Mycetes: a collective term for fungi, esp microscopic pathogenic fungi"
http://www.collinsdictionary.com/dictionary/english/mycetes

> "The solution emerges as soon as we turn to clinical experience which, combined with a wealth of descriptive elements, can only suggest that the mycetes or fungus is the sole agent responsible. It is the only one that can explain the incubation, rooting, course, and symptomatology for tumors. There are also several clinical considerations in favor of this theory.

> 1) Generally speaking, a bacteriological infection with a non-occasional pathogenic character causes elevated levels of exhaustion and the regression of exhaustion in a short time.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:28:31 No.11876446 Report

Quoted By: >>11876451 >>11876521

>>11876443

> It is accompanied by an elevated fever, it generally produces a pathology of the organs with related symptomatology which is globally stereotyped. Its action, therefore, takes place in a determined organ and in a precise temporal space.

> 2) A viral infection exclusively of the endocellular type is characterized by such rapidity, and ensuing hyper-pyretic climax (high fever), as to be sometimes instantaneous because of the viruses' small dimensions, which allow for immediate diffusion.

> Its action takes place and terminates in an extremely short time, with cellular effects that are exclusively necrotizing, but not in the direction of a metaplastic induction power."

> DEFINITION: "Necrotic tissue is dead tissue, which usually results from an inadequate local blood supply. Necrotic tissue contains dead cells and debris that are a consequence of the fragmentation of dying cells. Necrotic tissue changes color from red to brown or black/purple, as it becomes more dehydrated."
http://www.medscape.com/viewarticle/459733_5

> DEFINITION: "Metaplasia ... is the reversible replacement of one differentiated cell type with another mature differentiated cell type. The change from one type of cell to another may generally be a part of normal maturation process or caused by some sort of abnormal stimulus. In simplistic terms, it is as if the original cells are not robust enough to withstand the new environment, and so they change into another type more suited to the new environment. If the stimulus that caused metaplasia is removed or ceases, tissues return to their normal pattern of differentiation."
https://en.wikipedia.org/wiki/Metaplasia

> "In the cases where, instead, chronic pathology is produced, such as cirrhotic hepatitis, the causal agent can be found easily.

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!px/uPyl29A Tue 07 Jul 2020 07:30:40 No.11876451 Report

Quoted By: >>11876455 >>11876521

>>11876446

> 3) The morbid manifestations of bacterial origin with a more marked tendency to become chronic belong to that species of germs that show as mycetes, or, rather, their spores do, with a high content of lipids (fatty acids) in their structure.

> It is for this reason that the bacillus of a chronic bacterial disease such as tuberculosis is called a mycobacterium.

> 4) Even real oncogenic viruses (actually rare) for which an actual malignancy in animals has been observed show a high lipid content in their structure.

> From everything we have considered so far, the most logical and real cause of neoplastic proliferation would seem to be a fungus, and most likely one of those somehow pathogenic to humans.

> The World of Fungi

> As early as the nineteenth century, the German biologist Ernest Haeckele (1834-1919), when using the Linnean concept [37] that makes two great kingdoms out of all living things -- that of vegetables and that of animals -- reported difficulties of classification for all those microscopic organisms that because of the properties and characteristics could not be put into either the animal or the vegetable kingdom. He, therefore, proposed a third kingdom, that he called Protist.

O. Verona says:

> 'This vast and complex world ranges from entities with a subcellular structure -- and here we are at the limit of life -- such as viruses and viroidals, to get -- through microplasms -- to other organisms of higher organization: bacteria, actingomycetes, myxomycetes, fungi, protozoa, and if we want, even some microscopic algae.' [38]

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:33:45 No.11876455 Report

Quoted By: >>11876458 >>11876521

>>11876451

> The common element of all these organisms is the feeding system, which, save for a few exceptions, takes place with direct absorption of soluble organic compounds. That differentiates them from both animals, which nourish themselves by ingesting solid organic materials that are transformed with digestive processes, and from vegetables, which synthesize the organic substance from mineral compounds through light energy.

> Although perfected, the current tendency of biologists is to adopt the concept of the Third Kingdom. Some go even further, arguing how fungi must be allocated to a different classification.

Again, O. Verona:

> 'If we put in the first kingdom pluri-cellular organisms provided with photosynthetic abilities (plants) and in the second the organisms not provided with photosynthetic pigmentation (animals) -- both constructed of cells with distinct nuclei (eukarytotes), and additionally we put in another kingdom, finally, to possess a distinct nucleus.' [39]

> Furthermore, unlike all other micro-organisms, they possess a curious property, that of having a basic microscopic structure ... and at the same time the tendency to reach remarkable dimensions (even several kilograms) while they keep unchanged their ability to adapt and to reproduce at any size.

> In this way, therefore, they cannot be properly considered as organisms but as aggregates of cells of their own kind with an organismic behavior, since each cell keeps its potential for survival and reproduction intact and independent of the structure to which it belongs. Therefore, it is strikingly clear how very difficult it becomes to identify such complex living realities in all their biological processes. In fact, even today, there are huge gaps and approximations in the taxonomic characteristics used in mycology."

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:34:47 No.11876458 Report

Quoted By: >>11876459 >>11876521

>>11876455

Image Caption / Aside:

> "Typically, fungi start from spores, growing as filaments called hyphae, with a diameter of about 5-10 microns thick (it isn't that hyphae grow from a body; the fungus itself is a hypha).

> As hyphae grow, they continuously produce new ramifications.

> As hyphae of a single fungus come in contact with those of other fungine cellular units, they form an organism of bigger dimensions called a mycelium. The layer of mold on bread can give an example of this aggregation. All its mass is a single fungus but, if it is subdivided in smaller parts, still these form living, autonomous units.

> Hyphae grow at their apexes ... transporting their protoplasm (the internal, cellular substance) into the space where they grow.

> This mechanism allows a steady growth towards new nutritional areas, even through the penetration of solid surfaces, such as are the cell walls of plant and of living organisms."

Book continues ...

> "It is worth the trouble to stop and examine in greater depth this strange world with its peculiar characteristics, while attempting to highlight those elements that somehow pertain to the problems of oncology.

> 1) Fungi are heterotrophic organisms (they depend on ready-made food) and therefore they need pre-formed compounds to obtain carbon and nitrogen. The simple carbohydrates of these elements (for example monosaccharide glucose, fructose, and mannose) are the sugars that are the most utilized.

> This means that in their life cycle they depend for nutrition on other living beings which have to be exploited in various ways, both in a saprophytic (nourishment through organic waste) and in a parasitic manner (attaching themselves directly to the tissues of the host).

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:35:49 No.11876459 Report

Quoted By: >>11876461 >>11876521

>>11876458

> 2) They are classified as eumycetes with sexual reproduction (that is, perfect fungi) and as deuteromycetes with asexual reproduction that does not stem from any fecundation process.

In both cases, the reproductive cycle takes place through unicellular or pluricellular spores. [40]"

> DEFINITION: "Polymorphism [1] in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species. In order to be classified as such, morphs must occupy the same habitat at the same time and belong to a panmictic population (one with random mating).[2]"
https://en.wikipedia.org/wiki/Polymorphism_(biology)

> "The extreme complexity of the reproductive panorama of fungi is exceedingly interesting, because their very polymorphism highlights such biological variety that we can infer an unlimited adaptability and therefore an unlimited pathogenic potentiality. In this way, the great variety of reproductive manifestations (sexual, asexual, gemmation, which can often to be observed in a single mycetes) combined with great morph structural variety of the related organs, is geared to the creation of spores to which the continuity and spreading of the species is entrusted.

> 3) It is often possible to observe a particular phenomenon called heterocariosis in mycology, which is characterized by the coexistence of normal and mutated nuclei in cells that have undergone a hyphal fusion. Today there is great concern by the phytopathologists about the formation of individuals that are genetically quite different from the parents and which takes place through reproductive cycles termed parasexual."

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:36:50 No.11876461 Report

Quoted By: >>11876462 >>11876521

>>11876459

> DEFINITION: "Phytotherapy is the study of the use of extracts of natural origin as medicines or health-promoting agents. Phytotherapy medicines differ from plant-derived medicines in standard pharmacology. Where standard pharmacology isolates an active compound from a given plant, phytotherapy aims to preserve the complexity of substances from a given plant with relatively less processing."

> "The vast use of phyto drugs, in fact, has often caused mutations in the nuclei of many parasite fungi with the consequential formation of heterocarion. Sometimes these fungi are particularly virulent in their pathogenicity. [41]"

> "4) As a parasite, fungi can develop some specialized structures shaped like a roster of variable size from hyphas (the base implant). [42] These roster structures make penetration into the host possible.

> 5) The production of spores can be so abundant that each cycle always includes tens, hundreds, and even thousands of millions of elements that can be dispersed at a remarkable distance from their starting point. A small movement, for example, is sufficient to set off their immediate dispersal.

> 6) The spores possess a very strong resistance to external aggression, as they are capable of staying dormant for many years if the environmental conditions dictate it while preserving their regenerative potential unchanged.

> 7) The development coefficient of the hyphal apexes (the tips) after germination is extremely fast (100 microns per minute in an ideal environment), with a branching ability, and thus with the appearance of a new apex region, which in some cases takes only around 40-60 seconds. [43]

> 8) The shape of the fungus is never defined, as it is imposed by the environment in which the fungus develops.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:37:51 No.11876462 Report

Quoted By: >>11876463 >>11876521

>>11876461

> It is possible to observe, for example, the very same mycelium existing in a status of simple isolated hyphas in a liquid environment or existing in aggregations ever more solid and compact up to the formation of pseudo-parenchymas (stromas or supporting structures) and mycelial filaments and strings (rhizomorphs). [44]

> By the same token, it is possible to observe the same shape in different fungi where they must conform to the same environment (the phenomenon is usually called dimorphism).

> 9) The partial or total substitution of nourishing substances induces frequent mutations in fungi and that testifies to their marked adaptability to all substrata.

> 10) When precarious nutritional conditions exist, many fungi respond with hyphal fusion (between neighboring fungi), which allows them to explore the available material more easily and with more complete physiological processes. This property substitutes competition with cooperation and sets fungi aside from any other micro-organism. For this reason, some biologists call them social organisms. [45]

> 11) When a cell gets old or is damaged (for example, by toxic substances or drugs) many fungi whose intercellular septi are provided with pores react with the implementation of a defense process called protoplasmatic flux through which they transfer both the nucleus and the cytoplasm of the damaged cell into a healthy one while preserving all their biological potential unchanged.

> 12) How the development of hyphal ramification is regulated is unknown. [46] It consists of either a rhythmic development, or in the appearance of sectors that, while originating from the hyphal system, are nevertheless self-regulating, [47] that is, they are independent from the regulation and the behavior of the rest of the colony.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:38:52 No.11876463 Report

Quoted By: >>11876468 >>11876521

>>11876462

> 13) Fungi are able to implement an endless number of modifications to their own metabolism to overcome the defense mechanism of the host. These consist of plasmatic and biochemical actions as well as volumetric increments (hypertrophia) and numerical increments (hyperplasia) of the affected cells. [48]

> 14) They have exceptional aggressiveness. They attack not only plants but also animal tissue, food supplies, and even other fungi as well as protozoa, amoebas and nematodes.

> The hunt for nematodes, for example, takes place with special hyphal modifications that constitute veritable mycelial traps, which may be criss-crossed, viscous, or ring-shaped.

> These traps immobilize the worms which are subsequently invaded with hyphas. In some cases, the aggressive power of fungi is so high as to allow a cellular ring made of only three units to surround, imprison, and kill a prey in a short time despite its desperate wiggling.

> From the short notes given above, it would therefore seem appropriate to pay more attention to the world of fungi, which we have seen are living objects representing the twilight layer between plants and animals. Special attention is to be paid if we consider that both biologists and microbiologists, when called to describe or interpret the form, the physiology and the reproduction of a fungus, always show large knowledge gaps.

> It seems therefore very logical to assume that a cause of neoplastic proliferation could be a fungus -- the most powerful and most organized micro-organism known. Furthermore, the cause might be found in those imperfect fungi (so named because of our lack of knowledge about their biological processes) whose essential prerogative is in their ability to ferment."

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:40:14 No.11876468 Report

Quoted By: >>11876469 >>11876521

>>11876463

> DEFINITION: "Most of the so-called imperfect fungi, a group also called deuteromycetes, are those in which the sexual reproductive stages have not been observed. Most of these appear to be related to ascomycetes although some have clear affinities to the other phyla. The group of fungi from which a particular nonsexual strain has been derived usually can be determined by the features of its hyphae and asexual reproduction. It cannot, however, be classified by the standards of that group because the classification systems are based on the features related to sexual reproduction. One consequence of this system is that as sexual reproduction is discovered in an imperfect fungus, it may have two names assigned to different stages of its life cycle. There are some 17,000 described species of imperfect fungi ..."
http://www.mhhe.com/biosci/genbio/tlw3/eBridge/Chp15/15_6.pdf

> "The gravest disease of humanity may be hidden within the small group of pathogenic fungi. Perhaps the cause of cancer can finally be located with some simple deductions that may lead us to a solution to the problem.

> Pathogenic Mycetes in Humans

> When compared with the whole universe of fungi forms mycetes that are pathogenic for humans are not very numerous.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:41:16 No.11876469 Report

Quoted By: >>11876475 >>11876521

>>11876468

> They usually cause diseases called mycosis, which are commonly divided into superficial (when the infection is limited to the cutis, body, hair, hair of the head, and nails) and deep (when the infection attacks internal organs such as lung, intestine encephalus, bones, and others). The fungi are generally classified as:

> 1. Dermatorphytes, causing afflictions that are typical of the epidermis (tinea).

> 2. sporotrichum schenckii, which are also almost exclusively located on the epidermis.

> 3. Criptococcus neoformans, responsible for a diffused infection of the lung (the organisms are inhaled with dust) as well as chronic meningitis.

> 4. Histoplasma capsulatum, which in humans produces the nodular cutaneous form, mucous form, the pulmonary form, and the systemic form.

> 5. Actinomycetes, with pathogenic action on the cutis, lungs, and intestine.

> 6. Chrysosporium parvum (causal agent of the adiasphyromycosis), a cosmopolitan disease where the respiratory tract constitutes the primary and only localization of the infection.

> 7. Aspergillus fumigatus, cause of the Aspergillosis, whose most frequent location is in the lungs, followed by a secondary location in the cerebrum and in the kidneys.

> 8. Paracocci dioides brasiliensis, which causes the paracoccidioidomycosis, a primary pulmonary infection that can become diffused in immuno-depressed patients.

> 9. In recent years, Pheoiphomycosis, ialiphmycosis, pennicilinosis (marneffei), zigomicosis and other rare mycotic infections are acquiring more and more importance since they can be responsible for pathological scenarios that are sometimes very serious because of the compromised conditions of immunocompromised patients.

> 10. Candida, both as Albicans and as any other pathogenic stock which afflicts the cutis, nails, internal mucus membranes (oral cavity, vulvar vaginitis, urethritis, balanitis, perianal infection), bronchi and lungs.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:42:56 No.11876475 Report

Quoted By: >>11876477 >>11876521

>>11876469

> Candida is also responsible for causing generalized forms of septicemia of remarkable gravity."

> DEFINITION: "Septicemia is an infection of the blood, also known as bacteremia or blood poisoning ... It must be treated in the hospital. If left untreated, septicemia can progress into sepsis."
http://www.healthline.com/health/septicemia

> DEFINITION: "Sepsis is a life-threatening condition that arises when the body's response to infection injures its own tissues and organs.[1] Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion.[2] There may also be symptoms related to a specific infection, such as a cough with pneumonia, or painful urination with a kidney infection."

> "The gravest disease of humanity is, therefore, hidden within this grouping of fungi. Some further analysis will make it easier to identify the cause.

> Dermatorphytes and sporotrichum are responsible for a morbidity that is too specific. We know from experience that Actinomycetes, Criptococcus, Hystoplasm, Chrysosporium, Paracoccidioides and other causal agents of Pheoiphomycosis ialiphmycosis, pennicilinosis, zigomicosis are very rarely part of a pathological context. Finally, Aspergillus can be considered a variation of Candida. Only one of the six kinds described above remains as the sole responsible agent for tumors: Candida.

> To that end, it is useful to call the reader's attention to the fact that in recent years the infections spread by the Candida species (Albicans, Glabrata, Krusi, Parapsilosis, Tropicalis, and others) -- that is, systemic candidosis -- have been raised to great importance in oncology. These infections today represent, according to the majority of scholars, the main cause of morbidity and mortality in patients afflicted by neoplasias. It is sufficient to consider that Candida-related sepsis alone has increased 400 times in the last few years in American hospitals.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:44:01 No.11876477 Report

Quoted By: >>11876480 >>11876521

>>11876475

> Why is there such pathological parallelism in the evolution of cancer and Candida? Isn't it perhaps simpler to assume that the two converge up to the point of being considered the very same disease? Actually, if we stop and reflect for a moment on Candida's characteristics we observe many analogies with neoplastic disease. The most obvious of these are:

> a. ubiquitous rooting. No organ or tissue is spared
> b. constant lack of hyperpyrexia (high fever)
> c. sporadic involvement of muscles and nervous tissue
> d. invasiveness of the almost exclusive focal type
> e. progressive debilitation
> f. refractoriness to any treatment
> g. proliferation favored by a multiplicity of undifferentiated concomitant causes
> h. basic symptomatological configuration with structure tending to become chronic
> i. frequent formation of parparenchymal masses that are morphologically similar to neoplastic masses.

> Why Candida is Cancer

> Generally, mycetes have a recognized and almost unlimited ability to adapt, made possible by their seemingly endless ways of reacting to biological substrata, and ranging from simple metabolic variations to radical morphological changes.

> In the human organism, other than their presence in various forms, we can observe that mycetes have a variability of biological expression depending on the function of the tissue or organ they are interested in. The current classification into superficial and deep forms stems from this variability.

> The characteristics described above are the prerogatives of the entire fungin spectrum. However, they have particular relevance in Candida, as it is no doubt the most significant representative of the kind.

> It is enough to consider this fact: about 70 species are recognized as a saprophytic, that is, a micro-organism that gets its nourishment from decomposing substances and 20 as a pathogen.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:45:03 No.11876480 Report

Quoted By: >>11876483 >>11876521

>>11876477

> As far as the interaction of fungi with humans is concerned, should we be content only with the usual classification proposed, superficial and deep mycosis, which is exclusively founded on what can be directly observed? In other words, can we be sure that this wonder of adaptation called Candida cannot find a way to survive in more infinitesimal biological dimensions?

> Obviously not.

> Unfortunately. the technology available to medical science may not be able to see it in all its vital excursions and as a result may relegate it to more or less a dimension of semisaphrophytism, which may be very false and dangerous.

DEFINITION: "Saprophytism: the ability of certain plants to live in dead or decaying organic matter."
http://www.thefreedictionary.com/saprophytism

> Indeed, there is an exceptionally high pathogenic potential in this mycetes with the size of a few microns, which, although it cannot be found with the current tools of investigation, cannot be dismissed from the clinical point of view.

> In fact, we frequently observe recurrent candidoses that are so obstinate -- and for which the only evolution is markedly in an irreversible and chronic direction -- that they are insensitive to any medical treatment.

> This is because Candida, the moment it is attacked by the immune system of the host or by a conventional anti-mycotic treatment, defends itself by transforming into elements that are ever smaller and undifferentiated, while staying fully fecund up to the point of almost hiding its presence from both the hosting organism and diagnostic investigations.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:46:08 No.11876483 Report

Quoted By: >>11876484 >>11876521

>>11876480

> Its behavior also shows an 'elastic' nature: when rooting conditions are favorable it thrives on an epithelium (a vital surface), but as soon as the tissue reaction is engaged, it transforms itself massively into a less productive form but one which cannot be attacked, the spore. If sub-epithelial continuity solutions arise that are conjugated with a hypodermic areactivity [???], the spore is able to wedge in and then sink into the underlying connective tissue and hide in such a way as to be invulnerable and irreversible. In short, Candida takes advantage of a structural interchangeability that it utilizes according to the difficulties it encounters in its biological niche.

> In the soil, in the air, in the water and in vegetation -- that is, where there is no antibody reaction -- Candida is free to grow to a mature vegetative form. In epitheliums it takes on a mixed form which is reduced solely to the form of spores (at least in the initial phases when it penetrates to deeper levels).

> Again, Candida has an unlimited pathogenic potential which is underestimated, perhaps because of the way it is commonly described and understood, although there are already many studies that testify to its carcinogenic power.

> Why, one could ask, should we assume a different and enhanced activity for Candida Albicans, since it has been extensively described in these pathological manifestations?

> The answer is that it has been studied only within a pathogenic context, that is, only in relationship to the tissues that cover a diseased organism. In reality, Candida possesses an aggressive valence which is diversified as a function of the tissue it is interested in. It is only in the connective or in the connective environment -- and not in differentiated tissues -- that Candida finds the conditions for unlimited expansion.

> Over 50 years ago, Wilhelm Reich wrote:

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:47:10 No.11876484 Report

Quoted By: >>11876488 >>11876521

>>11876483

> 'If in the connective tissue which is directly in contact with the tumor the specific structures are disintegrated, the physiological barrier which normally exists between epithelial and connective tissue is destroyed and the cancer cells have free rein.' [49]

> This becomes even clearer if we stop for a moment to consider what the main function of the connective tissue is: that of carrying and supplying the cells of the entire organism with nourishing substances.

> DEFINITION: "Sui generis ... is a Latin phrase, meaning "of its (his, her, or their) own kind; in a class by itself; unique"

> In this context, in fact, it can be considered as an external environment sui generis next to the more differentiated cells such as those of the nerves and muscles; it is here where the competition for nourishment takes place.

> On the one hand, the cellular elements of the organism try to defeat all forms of invasion while on the other, the fungin cells try to absorb ever-growing quantities of nourishing substances, as they must obey the biological needs of the species which is that of tending to the formation of ever larger and spreading masses and colonies. This is a biological thrust sometimes capable of producing aggregates of unusual dimensions, the most striking example of all being the fungal colonies in the United States which cover 44 hectares of land.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:48:12 No.11876488 Report

Quoted By: >>11876490 >>11876521

>>11876484

> 'If in the connective tissue which is directly in contact with the tumor the specific structures are disintegrated, the physiological barrier which normally exists between epithelial and connective tissue is destroyed and the cancer cells have free rein.' [49]

> This becomes even clearer if we stop for a moment to consider what the main function of the connective tissue is: that of carrying and supplying the cells of the entire organism with nourishing substances.

> DEFINITION: "Sui generis ... is a Latin phrase, meaning "of its (his, her, or their) own kind; in a class by itself; unique"

> In this context, in fact, it can be considered as an external environment sui generis next to the more differentiated cells such as those of the nerves and muscles; it is here where the competition for nourishment takes place.

> On the one hand, the cellular elements of the organism try to defeat all forms of invasion while on the other, the fungin cells try to absorb ever-growing quantities of nourishing substances, as they must obey the biological needs of the species which is that of tending to the formation of ever larger and spreading masses and colonies. This is a biological thrust sometimes capable of producing aggregates of unusual dimensions, the most striking example of all being the fungal colonies in the United States which cover 44 hectares of land.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:49:14 No.11876490 Report

Quoted By: >>11876492 >>11876521

>>11876488

> Candida is Always Present in Cancer

> There are a large number of works that document the constant presence of the mycetes in the tissues of cancer patients, especially in terminal patients.

> In recent years, we have observed a crescendo of voices addressing this terrible fungus to the point of defining it as 'the most important and most urgent problem that oncology has to solve.' The following figures concerning the coexistence of Candida and cancer have been collected by several authors: [53]

> R.L. Hopfer: 79%
> U. Kaben: 80%
> W. T. Hughes: 91%
> T.E. Kiehn: 97%"

> "The percentages observed are truly impressive, especially when considering the difficulty of seeing Candida in the organic materials to be examined. This was also reported by R.S. Escuro, Z.O. Karaev, and T.J. Walsh. [54]

> The positive results quoted allow us to confirm that Candida is always present in the tissues of cancer patients. Not only that, but Candida species represent today, according to several scholars, the first cause of morbidity and mortality in patients affected by neoplasias of the hemolinphopoietic system. [55]

> O. Uzun even analyzed all data from l974 to 1999 concerning the presence of candidosis in patients and the prognostic factors including predictable elements of mortality and came to the conclusion that the global rate of mortality in cancer patients varies between 33% and 75% and that this is independent of the type of infecting Candida. [56]

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:50:16 No.11876492 Report

Quoted By: >>11876493 >>11876521

>>11876490

> The phenomenon is usually interpreted as a consequence of the weakening and of the exhaustion of the organism because of neoplastic lesions. Conversely, we have to believe that the aggression of Candida takes place in the carcinogenic sense after the superficial pathogenic phases -- that is, the classic epithelial candidosis -- in several stages:

> a) rooting in the deep connective tissue (in the various organs).
b) expansion with evoking of an organic reaction that attempts to encyst the fungin colonies, with the outcome being the formation of neoplasias.
c) growth both in the surrounding tissue and remotely (metastasis).
d) progressive exhaustion of the organism with consequential global organism invasion. This is the stage that is most commonly observed and that is considered 'opportunistic'.
e) exitus.

> In summary, Candida is not a post hoc but an ante hoc cause. Several works support what has been stated here concerning a causal link between Candida and cancer: [57]

> - A. Pedersen and J. Trotoux: The Formation of Epidermoidal Tongue Carcinoma.
> - K.V. Zhang and O'Grady: Oral Cavity's Neoplasias.
> - J.N. Hicks: Larynx's Neoplasia.
> - E.A. Field and F.R. Wang: Lung Cancer.
> - P. Joseph: Streaked Mixoma.
> - A. Rumi et al: Esophagus Cancer.
> - T. Taguchi: Intestinal Carcinoma.
> - V. Raina: Hodgkin's Disease.
> - M. Piazzi: Kaposi's Disease.
> - A. Mannell: Pancreas's Tumor.

> DEFINITION: "Carcinogenetic: of or pertaining to carcinogenesis; forming cancer cells."
https://en.wiktionary.org/wiki/carcinogenetic

> The considerations and the works cited above testify that Candida possesses a great carcinogenetic ability, and confirms that today it is no longer acceptable to conceive solely a pathogenic role for Candida that is consequential to a state of post-tumoral exhaustion.

> DEFINITION: "Prepose: to place before or in front of something"
http://www.merriam-webster.com/dictionary/prepose

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:51:43 No.11876493 Report

Quoted By: >>11876496 >>11876521

>>11876492

> Many amongst the authors we have cited and others that we have not cited [58] admit without hesitation to a direct causal role of the mycetes in the genesis of cancer, but the error they often make is that of believing Candida solely responsible for the production of substances that modify the genes that are preposed the functionality of the cell. This evaluation prevents them from attributing a direct responsibility to mycetes, and this is the aspect that would finally plough the way to the conclusive discovery of the cause of cancer.

> Because of the evidence that currently exists, it is not at all logical therefore to insist in seeing Candida as a micro-organism in the twilight zone between pathogenicity and harmlessness. Rather, it should be investigated as the sole, terrible causal generator of neoplasias."

A Very Unlikely Coincidence: A Corroboration of the Claim Through Alternative Means

http://www.bibliotecapleyades.net/salud/salud_defeatcancer30.htm

> The ancient Egyptians knew about the healing properties of anti-fungal substances and Indian books going back a thousand years actually recommend 'alkaline of strong potency' for treating cancer.

> In 1983, Simoncini treated an Italian man, Gennaro Sangermano, who had been given months to live with lung cancer. A few months later he wasn't dead, he was back to health and the cancer was gone.

> More success followed and Simoncini presented his findings to the Italian Department of Health in the hope that they would begin scientifically-approved trials to show that his treatment worked.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:52:46 No.11876496 Report

Quoted By: >>11876498 >>11876521

>>11876493

> But he was to learn the true scale of medical manipulation and deceit.

> The authorities not only ignored his documentation, he was disbarred from the Italian Medical Order for prescribing cures that had not been approved.

> Tullio Simoncini is, thankfully, no quitter and he has continued to circulate his work on the Internet and in public talks. I heard of him through Mike Lambert at the Shen Clinic and Simoncini spoke there while I was away in the United States.

> I know that he is having remarkable success in dramatically reducing and removing altogether even some real late stage cancers using sodium bicarbonate. This can take months in some cases, but in others, like breast cancer where the tumor is easily accessible, it can be days before it is no more.

> I wrote a newsletter last April about the fact that cancer is a fungus in an article about the findings of two British scientists and researchers, Professor Gerry Potter of the Cancer Drug Discovery Group and Professor Dan Burke.

> Their combined findings reveal the following ..."

> I recommend that if you do not understand this on the first try, read it over a few times until you get it. It's worth understanding!

> [1] "Cancer cells have a unique 'biomarker' that normal cells do not, an enzyme called CYP1B1 (pronounced sip-one-bee-one)."

Confirmed.

From http://jpet.aspetjournals.org/content/296/2/537.full:

> "The cytochrome P450 1B1 (CYP1B1) is involved in the metabolism of procarcinogens and xenobiotics. Human CYP1B1 protein has been detected in a variety of tumors but is not detected in adjacent normal tissues or in liver. This suggests that CYP1B1 could biotransform anticancer agents specifically in the target cells."

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:53:49 No.11876498 Report

Quoted By: >>11876501 >>11876521

>>11876496

> [2] "Enzymes are proteins that 'catalyze' (increase the rate of) chemical reactions."

This is true, of course.

> [3] "The CYP1B1 alters the chemical structure of something called salvestrols that are found naturally in many fruit and vegetables."

Traced back to a paper with additional sources:

http://truemedmd.com/wp-content/uploads/2013/06/Savestrol-Cases-Studies_JOM_2007_v22_n04_p177.pdf

> Salvestrols are a class of phytonutrients that, in humans, are metabolized by the tumour-specific CYP1B1 enzyme in cancer cells [1]-[8] to initiate a cascade of processes, including apoptosis, that result in the arrest or decline of the cancer. In this way Salvestrols are natural prodrugs as their activity hinges on activation by CYP1B1. [9][10]

> In their natural source Salvestrols form part of a plant’s defence mechanism. Some are hydrophilic while others are lipophilic but all are phytoalexins that are elicited by invading pathogens. For example, when a ripe fruit comes under attack by fungus the synthesis of a pathogen-specific Salvestrol is induced. The Salvestrol is synthesized at the site of the attack, typically the skin of the fruit or the root of the plant, and enters the pathogen.

Even more sources can be found here:

http://truemedmd.com/2013/06/salvestrols-for-cancer-survivors-jeffrey-dach/

> [4] "This chemical change turns the salvestrols into an agent that kills cancer cells, but does no harm to healthy cells ..."

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:54:52 No.11876501 Report

Quoted By: >>11876503 >>11876521

>>11876498

There is a graph of this here ...

http://www.salvestrol.ca/salvestrolinfohcp.asp

> [5] "The CYP1B1 enzyme appears only in cancer cells and it reacts with salvestrols in fruit and vegetables to create a chemical substance that kills only cancer cells."

There are many sites which repeat this same claim. Here's one of the more detailed examples.

http://www.salvestrol.ca/salvestrolinfohcp.asp

> "Salvestrols are essential phytonutrients supplied through our diet. They are otherwise chemically unrelated substances except for their reaction with a particular enzyme (CYP1B1) that has been established as a universal marker for cancer cells. When a salvestrol encounters the enzyme it is metabolized into a new compound which initiates cell apoptosis, a huge benefit because the enzyme is not present in healthy cells as can be seen in the graph to the right. The red line shows the devastating effect of salvestrols on cancer cells and the green line shows absolutely no effect upon healthy cells. The blue line shows a similar absence of an effect upon cells in which expression of CYP1B1 has been inhibited.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:55:53 No.11876503 Report

Quoted By: >>11876508 >>11876521

>>11876501

> The discovery of Salvestrols resulted from the convergence of two research paths: (1) Dan Burke's work trying to identify universal cancer markers, and (2) Gerry Potter's work designing prodrugs utilizing CYP enzymes to target cancer cells. While he was at the Institute for Cancer Research in London, Gerry, now a Professor of Medicinal Chemistry, had designed a prodrug that targeted CYP17. Aberaterone, as it is now known, has been producing such good results with prostate cancer that Johnson & Johnson recently bought the company that had licensed the rights for more than a billion dollars. Dan, a Professor of Pharmaceutical Metabolism and head of the School of Pharmacy, had demonstrated that another CYP enzyme (CYP1B1) was a universal marker for cancer cells, a result later confirmed by Dana-Farber at Harvard. When Gerry joined Dan at the University of de Montefort, Gerry designed a prodrug to target CYP1B1. That drug was also licensed to an American biotechnology company and is currently in clinical trials.

> Given that the drugs they had designed would not be available for many years, Gerry and Dan set about identifying natural compounds that could do the same job. Gerry had noticed that the drug he had designed was similar to natural compounds present in food. If suitable compounds could be identified, then the foods containing them could be promoted for a beneficial diet. Such compounds were found but, unfortunately, foods that should have had held high concentrations didn't due to modern farming and food production techniques which for various reasons removed them. Dan and Gerry therefore devised a dietary supplement that includes four of these compounds, now known as Salvestrols."

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:57:12 No.11876508 Report

Quoted By: >>11876511 >>11876521

>>11876503

> [6] "Salvestrols are the natural defense system in fruit and vegetables against fungal attacks and that's why you only find them in those species subject to fungus damage, like strawberries, blueberries, raspberries, grapes, blackcurrants, redcurrants, blackberries, cranberries, apples, pears, green vegetables (especially broccoli and the cabbage family), artichokes, red and yellow peppers, avocados, watercress, asparagus and aubergines."

Confirmed:

http://news.bbc.co.uk/2/hi/health/6987200.stm

> "Tangerine peel 'kills cancer' Tangerines

> A compound extracted from tangerine peel can kill certain human cancer cells, research shows.

> A team from Leicester School of Pharmacy found Salvestrol Q40 was turned into a toxic compound in cancer cells, destroying them.

> Salvestrol Q40 is found at higher concentrations in tangerine peel, than in the flesh of the fruit.

> The researchers suggest the modern trend to throw away peel may have contributed to a rise in some cancers.

> Lead researcher Dr Hoon Tan said his work was still at an early stage, but together with his colleagues he has formed a company to investigate further the potential to develop natural anti-cancer therapies.

> He said: 'It is very exciting to find a compound in food that can target cancers specifically.'

> Plant immune system

> Salvestrol 40 is a type of phytoalexin - a chemical produced by plants to repel attackers, such as insects or fungi.

> It is converted into a toxic compound by the P450 CYP1B1 enzyme, found in much higher levels in cancer cells.

> As a result, the researchers found, it proved to be 20 times more toxic to cancer cells than their healthy equivalents.

> Dr Tan said Salvestrol was found in other fruit and vegetables, such as the brassica family, which includes broccoli and brussels sprouts.

> However, the compound tends to be produced at higher levels when infection levels among crops are high.

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 07:58:17 No.11876511 Report

Quoted By: >>11876516 >>11876521

>>11876508

> Therefore, the use of modern pesticides and fungicides, which have cut the risk of infections, have also led to a drop in Salvestrol levels in food.

> Dr Julie Sharp, Cancer Research UK's science information manager, said: 'Many naturally occurring substances have anticancer properties, but while this research shows that salvestrols have an effect on cells in the laboratory, there is no evidence that they have a similar effect in patients.'

> 'Clinical trials would be needed to tell us if these substances could be developed into a cancer treatment.'"

Additional Coincidences

https://www.libertariannews.org/2015/02/02/cancer-a-yeast-fungus-gone-out-of-control/

> "If the assumption is made that cancer is a fungal infection, or at least that some cancers are the result of a fungal infection, all sorts of things begin to make sense.

> Cannabis has anti-fungal properties, particularly against candida albicans.

> If you look up natural treatments for candidemia, it reads like a natural cures list for cancer. Caprylic acid (unrefined coconut oil), Vitamin C, Vitamin D, Laetrile, cannabis oil, sodium bicarbonate, green tea, DMSO, even bee venom and certain snake venoms, they have all been touted as cancer cures, and all of them have antifungal properties.

> Oh, in case you were wondering, albicans grows on tobacco agar. As one study notes:

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 08:00:25 No.11876516 Report

Quoted By: >>11876518 >>11876521

>>11876511

> 'The predisposition of cigarette smokers for development of respiratory and oral bacterial infections is well documented. Cigarette smoke can also contribute to yeast infection.'"

> "Most yeast infections are caused by a type of yeast called Candida albicans." http://www.webmd.com/women/tc/vaginal-yeast-infections-topic-overview

> "Boy, it sure is an odd coincidence that things which promote cancer also seem to promote fungal infections, no? Did you know that a standardized way of inducing cancer in a laboratory rat is to inoculate the rat with aflatoxin b1, a fungal mycotoxin. Let me repeat that. We induce mycotoxicoses in rats by injecting them with fungal mycotoxin, and then we call the resulting condition of that cancer.

> An article in the New York Times notes:

> 'The old view is that cancer is a linear process,' said Dr. Barnett Kramer, associate director for disease prevention at the National Institutes of Health. 'A cell acquired a mutation, and little by little it acquired more and more mutations. Mutations are not supposed to revert spontaneously.'

> Indeed, they are not. Of course, fugal infections can easily account for this phenomena of cancer. The article talks about how routine screening for cancer found many cancers that, 'were destined to stop growing on their own or shrink, or even, at least in the case of some breast cancers, disappear.'*

!px/uPyl29A

!px/uPyl29A Tue 07 Jul 2020 08:01:27 No.11876518 Report

Quoted By: >>11876521

>>11876516

> The American Thoratic Society, a completely mainstream entity, has this to say about Aspergillosis:

> 'Aspergillosis generally starts out as a spot in your lung called a lung 'nodule'. (This nodule can be mistaken for lung cancer or tuberculosis)."

> DEFINITION: "Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. The majority of cases occur in people with underlying illnesses such as tuberculosis or chronic obstructive pulmonary disease (COPD), but with otherwise healthy immune systems."
https://en.wikipedia.org/wiki/Aspergillosis

> "The symptoms of fungal infection and cancer are virtually indistinguishable. That’s because there is no difference. A fungal infection presents in an identical way to cancer, because it is 'cancer.' In fact, the biopsy markers that are used to diagnose cancer are often the same as those for diagnosing a fungal infection.

> So here we have a situation where a disease (with no known cause) acts so much like another disease (one that has a known cause) that it can be mistaken for it. It responds to exactly the same treatment as the disease with a known cause. We also frequently find the disease with a known cause inside the tumors supposedly caused by the disease with no known cause.

> Perhaps if it walks like a duck, it looks like a duck and it quacks like a duck."

Anonymous

View Same Google iqdb SauceNAO 0a1.jpg, 80KiB, 643x820

Anonymous Tue 07 Jul 2020 08:05:31 No.11876521 Report

Quoted By: >>11877360

>>11876518
>>11876516
>>11876511
>>11876508
>>11876503
>>11876501
>>11876498
>>11876496
>>11876493
>>11876492
>>11876490
>>11876488
>>11876484
>>11876483
>>11876480
>>11876477
>>11876475
>>11876469
>>11876468
>>11876463
>>11876462
>>11876461
>>11876459
>>11876458
>>11876455
>>11876451
>>11876446
>>11876443
>>11876440
>>11876294

Anonymous

Anonymous Tue 07 Jul 2020 09:38:12 No.11876655 Report

Quoted By: >>11876661 >>11878109

I'm a mathfag and don't understand everything I read here, but this is an interesting thread.
Is the OP chart any good, or is it useless as >>11876257 suggests?

Anonymous

Anonymous Tue 07 Jul 2020 09:41:08 No.11876661 Report

Quoted By: >>11877701

>>11876655
Its terrible and was undoubtedly created by a cmol brainlet

Anonymous

Anonymous Tue 07 Jul 2020 09:53:23 No.11876688 Report

Quoted By: >>11876736

this thread is insane mods need to ban this guy.

Anonymous

Anonymous Tue 07 Jul 2020 10:00:41 No.11876699 Report

Quoted By: >>11877365

>>11876440
So... We will be back to shit baths like in medieval times to cure certain diseases?

Anonymous

Anonymous Tue 07 Jul 2020 10:20:51 No.11876736 Report

Quoted By: >>11876739

>>11876688
wdym?
What's the problem? Is it schizo?

Anonymous

Anonymous Tue 07 Jul 2020 10:22:31 No.11876739 Report

Quoted By:

>>11876736
Copy and pasting his blog into a thread is the most schizo thing imaginable.

Anonymous

View Same Google iqdb SauceNAO Yes.png, 270KiB, 680x709

Anonymous Tue 07 Jul 2020 14:56:53 No.11877360 Report

Quoted By:

>>11876521

Anonymous

View Same Google iqdb SauceNAO 1565706926675.png, 286KiB, 810x1600

Anonymous Tue 07 Jul 2020 14:58:07 No.11877365 Report

Quoted By:

>>11876699
>We will be back to shit baths like in medieval times to cure certain diseases?
If you're Christian, sure.

Anonymous

Anonymous Tue 07 Jul 2020 15:55:29 No.11877577 Report

Quoted By:

>>11876153
Daily reminder, radiation caused disease is not a cancer.

Anonymous

Anonymous Tue 07 Jul 2020 16:31:22 No.11877701 Report

Quoted By:

>>11876661
>list of books about cellular biology was probably created by a cellular biology graduate
real big brain deduction right here

Anonymous

Anonymous Tue 07 Jul 2020 18:50:21 No.11878109 Report

Quoted By:

>>11876655
You're confused and have misunderstood. >>11876257 was being sarcastic and wasn't referring to OP's pic (since it's not about cancer - it's just a /sci/ biology guide) but rather to OP's text - he was implying that OP had written something science-related about cancer (which he hadn't) and that OP's cancer-related science text was scientifically superior to >>11876154 (which of course makes no sense at all since OP merely wrote a statement about cancer; OP didn't provide any clues or ideas on how to cure it, or anything at all which could contribute towards a better scientific understanding of cancer), while simulataneously implying that fungus image was worthless in terms of science.

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