Placebo effect in active groups?

No.11816168 ViewReplyOriginalReport
So let's say a control group had a specific side effect rate of 2% and the active group had 3.5% for the same side effect.

Can't it be assumed that there is a possibility that the side effect rate caused by the actual drug itself may be lower than 3.5% because of some people experiencing a placebo effect in the active group as well?