>>11798690As you mentioned, Mengele was a sadist and it's the strongest case for ethics in medicine and experimentation in general. If you let nutjobs like him do whatever they want, there will be a lot of nutjobs wanting to do the same, and another group of nutjobs that won't be sadists but will treat anything as a test subject. This would be reasonable on any other discipline (like, I dont know, chemistry) because the tests aren't done on living things that are irreparably lost or irreparably damaged once you fail them. This is actually good for the scientific progress since someone who has infinite resources will do an approach more on trial and error and this could have devastating effects on human life due to accidents. If your resources are limited or extremely valuable, your approach will be extremely scientific and "by the book".
Essentially, if you let anyone do what they want, they will do horrible shit and may fail spectacularly wiping out humanity (coronavirus anyone?). If you force them to justify what the fuck they are doing, it's going to be a lot more ordered. Yes, humanity will progress on a slower pace, but it will progress nonetheless.