>>11726793The first guy on project manhigh had the pressure seal on his glove go bad while he was riding up to the edge of the atmosphere to test the survivability of bailing out from that altitude.
His hand swelled up and turned beet read, and he lost some feeling, but he didn't bother reporting it until after he landed because it wasn't worth scrubbing the mission.
Also pressure suit failures in test chambers and other high altitude flights.
They're usually designed with multiple seals too, so even if you do have a breach in your suit, its contained in sections.
The real neat stuff is the skin suits based off compression bandages for burn victims that they're playing with. All you need is to keep the head and chest pressurized so your lungs work, but the rest of your body can be exposed to hard vacuum without anything worse than blood blisters where it bunches up around the joints.