>>11706189From what? Being missing not, there's a reason for one X individuals.
Everything else can be repaired to a degree.
Single strand break, double strand break, missing parts like with CRISPR/Cas9 treatment, replication fork breaks are essentially half of the chromosome missing and those can be repaired or "regenerate".
In all those instances the chromosome ends abruptly, so it can be recognized as faulty, with another one as basis for filling in the blanks, none of those are "regenerated" from new" or "out of nothing".