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>Yohimbine is analpha-2 adrenergic antagonist, and has been used in a variety of research projects. It is a veterinary drug used to reverse sedation in dogs and deer. While yohimbine behaves as anaphrodisiacin some mammals, it does not do so in humans. It has been prescribed as a treatment forerectile dysfunction, but its reported clinical benefits were modest and it has largely been superseded by thePDE5 inhibitorclass of drugs. Substances which have purported to be extracts from the yohimbe tree have been marketed as dietary supplements for various purposes, but they contain highly variable amounts of yohimbine, if any; no published scientific evidence supports their efficacy.
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