>>11645579serotonin (mdma mainly just releases it in vast quantities) and other serotonin acting drugs damage the cardiovascular system. 5ht2b is actually fully implicated in cardiovascular damage and multiple prescription medications that acted on this receptor were banned. alexander shulgin did mdma and a lot of psychedelics but kept his ability to think and reason for the majority of his life but it really fell off towards the end according to his wiki
pic related is a study of serotonin axons in nonhuman primates before and after mdma in two parts of the brain (different parts have different degrees of damage and repair). there was also a study in rats that showed effectively the same thing. it was found that some parts of the brain after the mdma damage actually repaired somewhat but didn't have close to the same amount of axons but instead had thicker and stronger axons to compensate. experience wise per users, the first time you do molly the strongest it is and the latter times you do it the effects are diminished relatively.
it has been called a "miracle drug" for PTSD according to MAPS and is being researched for this. other than that nothing has been proven for its therapeutic uses
