We are about to see a real life experiment unfold.
The President of Brazil is dead-set against shutdowns and quarantines. First he tried to stop governors from implementing them. Now he has fired his health minister as part of his full-on war against lockdown measures.

Other denialists like Trump have caved in to scientific advice, but not Bolsonaro.
What will happen in Brazil?

https://www.breitbart.com/national-security/2020/04/17/bolsonaro-fires-brazilian-health-minister-we-need-to-return-to-normal/
>Brazilian President Jair Bolsonaro fired Health Minister Luiz Henrique Mandetta on Thursday on the grounds that Mandetta did not appreciate the need to end coronavirus lockdowns and restart Brazil’s economy as soon as possible.

>“We need to return to normal, not as fast as possible, but we need to start having some flexibility,” Bolsonaro said.

>Reuters anticipated Bolsonaro would lose the political argument he has engaged in, describing “pot-banging protests” against his firing of Mandetta and recalling fierce criticism of the Brazilian president for underestimating what he described as “a little flu.” Reuters reported polls that showed the Health Ministry enjoying 76 percent approval from the public under Mandetta, while Bolsonaro’s handling of the pandemic drew only 33 percent support.

>“Do not think we are past a peak in growth of the virus. The health system is still not prepared for an acceleration,” Mandetta warned in his parting remarks.

>Bolsonaro named oncologist Nelson Luiz Sperle Teich, a consultant to Bolsonaro’s 2018 presidential campaign and a consultant to the Health Ministry during the pandemic, as the new health minister.

>“There is complete alignment between me and the president, and the entire ministry group, that what we are really doing here is working to get society back to normal life faster,” Teich said.