/sci/ - Science & Math » Thread #11552581

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Organic Chemstry Synthesis

Anonymous Fri 10 Apr 22:48:12 2020 No.11552581 View Reply Original Report

Quoted By: >>11552591 >>11552611 >>11552669 >>11552687

How would you solve this?

Anonymous

Anonymous Fri 10 Apr 2020 22:52:49 No.11552591 Report

Quoted By: >>11552602

>>11552581
Sleep with the prof, zoomie.

Anonymous

Anonymous Fri 10 Apr 2020 22:56:25 No.11552602 Report

Quoted By:

>>11552591
I'll sleep with you if you tell me how to solve this

Anonymous

Anonymous Fri 10 Apr 2020 23:00:22 No.11552611 Report

Quoted By: >>11552645

>>11552581
stickem together

Anonymous

Anonymous Fri 10 Apr 2020 23:07:19 No.11552645 Report

Quoted By:

>>11552611
How would I add the extra shit? I figure I probably have to protect the ketone with an acetal while I do it, but I'm not sure what reagents to use.

Anonymous

Anonymous Fri 10 Apr 2020 23:17:53 No.11552669 Report

Quoted By: >>11552687

>>11552581
could use a grignard reagent with the ketone group protected by an acetal, then deprotect

Anonymous

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Anonymous Fri 10 Apr 2020 23:26:56 No.11552687 Report

Quoted By: >>11552713

>>11552669
>>11552581
Something like this, here I drew it out for you and everything

Anonymous

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Anonymous Fri 10 Apr 2020 23:39:28 No.11552713 Report

Quoted By:

>>11552687
thanks man I really appreciate it. I attempted it myself but yours is obviously a lot better because it is one step

Anonymous

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Anonymous Fri 10 Apr 2020 23:53:40 No.11552745 Report

Quoted By: >>11552768 >>11553694

One more problem I was having trouble coming up with the mechanism for.

Anonymous

Anonymous Sat 11 Apr 2020 00:05:31 No.11552768 Report

Quoted By: >>11552829

>>11552745
If I had to guess it would be deprotonation of the oh with sodium methoxide then SnAr
Not 100% on that though

Anonymous

Anonymous Sat 11 Apr 2020 00:32:57 No.11552829 Report

Quoted By:

>>11552768
Thanks for the help brother. Here is a steam key as a reward:

LFICC-L8M90-L309M

Anonymous

Anonymous Sat 11 Apr 2020 06:50:55 No.11553694 Report

Quoted By:

>>11552745
allsmiles.jpg

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