Where did the new plague come from? Is it evolved from SARS? SARSr-RATg13? Now they're saying it may have come from a Pangolin.
Conservation of ORF sequences in a virus is to be expected, especially in an RNA virus like corona. But what about opportunistic indels at critical binding sites and insertion sequences right before the S domain cleavage site? Why are machinery sequences more similar to SARS, but structurally it is more similar to SARSr-RATg13?
Could what we have now resulted from random mutations of past viruses, or cross infection of the two? Or could they have been combined in a lab to create a more virulent strain, altering spike regions and using a viral template like SARSr-RATg13 to be less recognizable in the host. Who knows? Gimme your thoughts!
Conservation of ORF sequences in a virus is to be expected, especially in an RNA virus like corona. But what about opportunistic indels at critical binding sites and insertion sequences right before the S domain cleavage site? Why are machinery sequences more similar to SARS, but structurally it is more similar to SARSr-RATg13?
Could what we have now resulted from random mutations of past viruses, or cross infection of the two? Or could they have been combined in a lab to create a more virulent strain, altering spike regions and using a viral template like SARSr-RATg13 to be less recognizable in the host. Who knows? Gimme your thoughts!
