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If it's hard science then its ok (not good). If it's not be wary of the results and assume they are wrong until a replication study is performed or some similar result is obtained. Also a good tell mark for individual researches is to check their publication history. If it looks like they churn out a shit ton of papers on what seems to be a highly iterated experiment, their research is probably garbage. Gauss' advice is best, Few but Ripe.